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Policy Papers and Issue Briefs
 
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Publications from the Microbicides Field
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IPM - Supported Scientific Papers & Articles
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Annual Reports    


If you would like to request hard copies of any of these publications please send an email to lmichel@ipm-microbicides.org. Please indicate the publication, the language(s), and the approximate timeframe in which you would like to receive the materials.


IPM Research Featured in Groundbreaking HIV Resource

IPM researchers have authored a chapter in a comprehensive new HIV prevention, care and treatment guide published by the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF).

The guide, From the Ground Up: Building Comprehensive HIV/AIDS Care Programs in Resource-Limited Settings, features the work of 230 public health experts from around the world. It builds on lessons learned from the last 20 years in HIV prevention, care and treatment. The foundation unveiled the guide Aug. 5 at the International AIDS Conference in Mexico City. For additional information click here.



Policy Papers and Issue Briefs

The publications listed below are available in Adobe PDF format. (Click here if you need to download a free version of Adobe Reader.)

IPM Microbicides brochure
English (February 2009)
Identifying Optimal Strategies for Microbicide Distribution in India and South Africa
English | French | Spanish (December 2008)
Appendices (English)
HIV/AIDS and the Millennium Development Goals: Microbicides and the Need for Long-Term Prevention
English (May 2009)
Guidelines for Conducting IPM Clinical Trials, 2nd edition
English | French | Spanish | German (October 2008)
IPM Consensus Statement on Resistance (October 2008)
English | French | Spanish | German
IPM brochure (May 2009)
English | French | Spanish | German
Issue Brief on Microbicide Research and Development
English | French | Spanish (February 2008)
Issue Brief on IPM Clinical Trials
English | French | Spanish (February 2008)
Planning for Microbicide Access in Developing Countries: Lessons from the Introduction of Contraceptive Technologies (July 2007)
Reviewing the UNGASS Declaration of Commitment on HIV and AIDS: The Need for Microbicides (June 2006)

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Fact Sheets

The publications listed below are available in Adobe PDF format. (Click here if you need to download a free version of Adobe Reader.)

Microbicides Overview (March 2009)
English | French | Spanish | German
The Need for Microbicides (March 2009)
English | French | Spanish | German
About IPM (February 2008)
English | French | Spanish | German
Microbicides: An Essential HIV Prevention Strategy for Achieving the Millennium Development Goals (July 2008)
English | French | Spanish | German
IPM Clinical Trials (December 2008)
English | French | Spanish
Women and HIV/AIDS (March 2009)
English | French | Spanish | German

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Annual Reports

The publications listed below are available in Adobe PDF format. (Click here if you need to download a free version of Adobe Reader.)

2008 Annual Report
2007 Annual Report
2007 Annual Report (French)
2007 Annual Report (Spanish)
2006 Annual Report
2006 Annual Report (French)
2006 Annual Report (Spanish)
2005 Annual Report
2005 Annual Report (French)
2004 Annual Report
2004 Annual Report (French)

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Publications from the Microbicides Field

The publications listed below are available in Adobe PDF format. (Click here if you need to download a free version of Adobe Reader.)

IPM and GCM: Working in Europe to Make Microbicides a Reality (December 2006)
Paving the Path: Preparing for Microbicide Introduction (2004)

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IPM - Supported Scientific Papers and Articles

Title Author(s) Publication Date
Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy HIV-negative women
AIDS
Nel AM, Coplan P, van de Wijgert JH, Kapiga SH, von Mollendorf C, Geubbels E, Vyankandondera J, Rees HV, Masenga G, Kiwelu I, Moyes J, Smythe SC In press
Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women
J Acquir Immune Defic Syndr
Nel A, Smythe S, Young K, Malcolm K, McCoy C, Rosenberg Z, Romano J In press
Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring
AIDS Res Hu Retro
Romano J, Variano B, Coplan P, Van Roey J, Douville K, Rosenberg Z, Temmerman M, Verstraelen H, Van Bortel L, Weyers S, Mitchnick M In press
Characterization of Vaginal Transmission of a Simian Human Immunodeficiency Virus (SHIV) Encoding the Reverse Transcriptase Gene from HIV-1 in Chinese Rhesus Macaques
Virology
Pal R, Nuttall J, Galmin L, Weiss D, Chung H-K, Romano J In press
The Future of HIV Microbicides: Challenges and Opportunities (pdf)
Antivir Chem Chemother
Garg AB, Nuttall J, Romano J April 2009
Safety Evaluation of 1% Tenofovir Gel in Healthy Men.
Int J STD AIDS
Schwartz JL, Poindexter A, Wheeless A, Mauck C, Callahan M In press

Inhibition of Human Immunodeficiency Virus Type 1 Infection by the Candidate Microbicide Dapivirine, a Nonnucleoside Reverse Transcriptase Inhibitor (abstract)
Antimicrob Agents Chemother

Fletcher P, Harman S, Azijn H, Armanasco N, Manlow P, Perumal D, de Bethune M-P, Nuttall J, Romano J, Shattock R February 2009
Microbicide delivery: formulation technologies and strategies. (abstract)
Curr Opin HIV AIDS
Romano J, Malcolm RK, Garg S, Rohan LC, Kaptur PE August 2008

Vaginal Microbicides - What does the future hold? (pdf)

Cates W. and Rosenberg Z. April 2008
The paradoxical effect of using antiretroviral-based microbicides to control HIV epidemics. Proc Natl Acad Sci USA. 2008;105(28):9835-40. Wilson DP, Coplan PM, Wainberg MA, Blower SM. 2008
Polyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1. J Pharm Sci. 2008;97(10):4228-39. Gupta KM, Pearce SM, Poursaid AE, Aliyar HA, Tresco PA, Mitchnick MA, et al. 2008
Concentrations of Dapivirine in the Rhesus Macaque and Rabbit Following Once Daily Intravaginal Administration of a Gel Formulation of [14C]Dapivirine for 7 Days (abstract)
pubmed.gov
Nuttall JP, Thake DC, Lewis MG, Ferkany JW, Romano JW, and Mitchnick MA December 2007
The Future of HIV Prevention: Prospects for an Effective Anti-HIV Microbicide
(pdf)
Infectious Disease Clinics of North America
J. Nuttall, J. Romano, K. Douville, C. Galbreath, A. Nel, W. Heyward, M. Mitchnick, S. Walker and Z. Rosenberg March 2007
Characterization of silicone elastomer vaginal rings containing HIV microbicide TMC120 by Raman spectroscopy (abstract)
Journal of Pharmacy and Pharmacology
S.E. Bell, A.C. Dennis, L.A. Fido, R.K. Malcolm, M.S.N. Sirimuthu, C.F. Toner and A.D. Woolfson February 2007
Microbicides for HIV/AIDS. 2. Electrophoretic Fingerprinting of CD4+ T-Cell Model Systems (abstract)
Langmuir: The American Chemical Society Journal of Surfaces and Colloids
D. Fairhurst, R.L. Rowell, I.M. Monahan, S. Key, D. Stieh, F. McNeil-Watson, A. Morfesis, M. Mitchnick and R.A. Shattock 27 February 2007
Challenges of producing a drug primarily for use in developing countries: miocrobicides for HIV prevention. Therapy. 2007;4(6):725-30. Nuttall J, Douville K, Galbreath C, Walker S, Norick P, Rosenberg Z. 2007
Temperature and pH sensitive hydrogels: an approach towards smart semen-triggered vaginal microbicidal vehicles. J Pharm Sci. 2007;96(3):670-81. Gupta KM, Barnes SR, Tangaro RA, Roberts MC, Owen DH, Katz DF, et al. 2007
Intravaginal ring delivery of the reverse transcriptase inhibitor TMC120 as an HIV microbicide (abstract)
International Journal of Pharmaceutics
A.D. Woolfson, R.K. Malcolm, R.J. Morrow, C.F. Toner and S.D. McCullagh 15 November 2006
Preparing for microbicide trials in Rwanda: Focus group discussions with Rwandan women and men (abstract)
Culture, Health & Sexuality
N. Veldhuijzen, J. Nyinawabega, M. Umulisa, B. Kankindi, E. Geubbels, P. Basinga, J. Vyankandondera and J. Van De Wijgert September-October 2006
Is HIV drug resistance a limiting factor in the development of anti-HIV NNRTI and NRTI-based vaginal microbicide strategies? (abstract)
Antiviral Research
J. Martinez, P. Coplan and M.A. Wainberg September 2006
Challenges to microbicide introduction in South Africa (abstract)
Social Science & Medicine
P. Orner, J. Harries, D. Cooper, J. Moodley, M. Hoffman, J. Becker, E. McGrory, R. Dabash and H. Bracken August 2006
Microbicides for the prevention of HIV infection in women: an overview of recent trials. Curr Opin HIV AIDS. 2006;1(6):514-9. Rosenberg Z, Nel A, Heyward W, Mitchnick M. 2006
Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings (abstract)
Journal of Antimicrobial Chemotherapy
R.K. Malcolm, A.D. Woolfson, C.F. Toner, R.J. Morrow and S.D. McCullagh 9 September 2005
Microbicides for HIV/AIDS. 1. Electrophoretic Fingerprinting the H9 Cell Model System (abstract)
Langmuir: The American Chemical Society Journal of Surfaces and Colloids
R. Rowell, D. Fairhurst, S. Key, A. Morfesis, I.M. Monahan, M. Mitchnick and R. Shattock 24 June 2005
Manufacturing Microbicides (pdf)
Impact 10: HIV Prevention – Condoms and Beyond
Z. Rosenberg June 2005
Strengthening Regulatory Capacity for Microbicides in Southern Africa (pdf)
The Microbicide Quarterly
T. Farley, I. Malonza and P. Coplan April-June 2005
Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development. Protein Expr Purif. 2005;39(2):229-36. Colleluori DM, Tien D, Kang F, Pagliei T, Kuss R, McCormick T, et al. 2005
Regulatory Challenges in Microbicide Development (pdf)
Science
P. Coplan, M. Mitchnick and Z. Rosenberg 25 June 2004
 
 
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